Figure 7.
Kinetics of thrombocyte recruitment of growing thrombus. (A) Time-lapse images captured from the real-time video of thrombus formation in zebrafish. Arrows mark the initiation of thrombus. Orange and greenish-yellow colors in the thrombus represent the dual dye-labeled and single dye-labeled thrombocytes/platelets respectively. (B) Schematic representation of growing thrombus (corresponding to time-lapse images shown in panel A) in an artery with initiating young thrombocyte (Y) clusters at the site of laser injury (L) followed by mixture of Y and mature thrombocyte (M) clusters. EC indicates endothelial cell; SE, subendothelial matrix; E, erythrocytes. Arrows show the direction of blood flow.