Effect of wild-type polymorphic HIV-1 peptides derived from their inhibitory HIV-1 peptide regions on the inhibition of Ab-induced platelet fragmentation. Peptides were preincubated with Ab for 15 minutes at 37°C prior to addition of the combined reagents to gel-filtered platelets (as in Figure 1). □ and ▪refer to preincubation with molar peptide/Ab ratios of 1:100 and 1:10, respectively. C indicates control IgG; P, patient IgG; Ph, phage peptide PHC39; HR3, HIV-1 wild-type peptide HI9R3; PHR3 and P39, reported polymorphic peptides of HI9R3 and PHC39, respectively (Table 1); Env, irrelevant conserved region of env (514-523). N=4. SEM is given.