Figure 7.
Expression of vascular-specific genes in cloche mutants at 22 to 24 hpf. (A-B) etsrp expression in the vasculature of wild-type siblings (A) and clo–/– embryos (B). Note that only a few etsrp-expressing cells in the cardinal vein plexus region are remaining in clo mutant embryos. (C-D) dusp5 expression in wild-type siblings (C) and clo–/– embryos (D). Note that only a few cells with faint dusp5 expression in the cardinal vein plexus region are remaining in clo mutant embryos. (E-F) cdh5 mRNA expression in wild-type siblings (E) and clo–/– embryos (F). Note that only a few cdh5-expressing cells in the cardinal vein plexus region are remaining in clo mutant embryos. (G-H) aqp8 expression in wild-type siblings (G) and clo–/– embryos (H). Note that only a few aqp8-expressing cells in the cardinal vein plexus region are remaining in clo mutant embryos. (I-J) admr expression in wild-type siblings (I) and clo–/– embryos (J). Note that only a few cells with a very faint admr expression in the cardinal vein plexus region are remaining in clo mutant embryos. (K-L) crl expression in wild-type siblings (K) and clo–/– embryos (L). Note that no crl-expressing cells are remaining in clo mutant embryos.