High specific lysis of RHAMM/CD168 R3-pulsed T2 cells and AML DCs in contrast to unmanipulated AML blasts as evaluated by chromium-51 release assay. Stimulated R3-primed CD8⁺ T cells were able to recognize AML blasts at a certain level, but AML DCs killed to 100% at an E/T ratio of 10:1. Primed T lymphocytes were also able to lyse R3-pulsed T2 cells. T2 cells were used as a negative control.