LDA analysis in V_H3-21⁺ and non-V_H3-21 B-CLL. (A) Genes included in the LDA class discriminator. The expression matrix shows the 57 probes that are reliably differentially expressed between the 2 groups, V_H3-21⁺ B-CLL and non-V_H3-21 B-CLL. (B) LDA of V_H3-21⁺ and non-V_H3-21 B-CLL. Red squares represent V_H3-21⁺ samples; blue squares, non-V_H3-21 samples. LDA was applied to the data of the 39 samples by the 57-probe set. Linear discriminants were determined for each sample and plotted. The prediction rate for samples with known class was 100% (P = .01). The median false discovery rate for this predictor was 1.7%.