Plot of transverse relaxivity R2 (1/T2) versus biopsy-measured HIC in 20 patients (22 biopsies). R value was 0.98, and dotted lines indicate 95% prediction intervals for the regression. Average R2 value for 13 healthy controls is shown by ○, plotted using an HIC value estimated from normative data (no biopsy). Repeat MRI and biopsy examinations as well as control data were excluded from statistical calculations.