Figure 2.
Kaplan-Meier curves (univariate analysis). Kaplan-Meier curves (univariate analysis) for cases with or without CD10 expression (A), CD20 expression (B), MUM1/IRF4 expression (C), BCL-2 expression (D), and for the 3 patterns according to Chang et al20 (E). In this model, pattern A indicates a GC B-cell pattern (expression of GC B-cell markers such as CD10 and/or BCL-6 but not of activation markers such as MUM1/IRF4 or CD138/Syn-1). Pattern B indicates an activated GC B-cell pattern (expression of at least one GC B-cell marker and of one activation marker). Pattern C indicates an activated non-GC B-cell pattern (expression of MUM1/IRF4 and/or CD138/Syn-1 but not of GC B-cell markers). For all Kaplan-Meier statistics, only patients with a curative chemotherapy were analyzed (n = 74).