PARP expression levels in different types of childhood acute leukemia and in drug-resistant versus -sensitive childhood ALL. (A) PARP expression in different types of childhood acute leukemia. Each dot represents an individual patient and the horizontal bar represents the median protein level. Protein expression level of PARP was quantitated in 28 B-lineage ALL samples (○), 15 T-lineage ALL samples (•) and 10 AML samples (▾). (B) PARP expression versus in vitro PRED, VCR, and ASP (PVA) resistance in childhood acute lymphoblastic leukemia. The protein expression level of PARP quantitated in 21 PVA-sensitive (S) and 22 PVA-resistant (R) patients with B-lineage ALL (○) or T-lineage ALL (•). ^*Statistically significant after Bonferroni correction for multiple comparisons. AU indicates arbitrary units.