Procaspase-2 expression levels in different types of childhood acute leukemia and in drug-resistant versus -sensitive childhood ALL. (A) Procaspase-2 expression in different types of childhood acute leukemia. Each dot represents an individual patient and the horizontal bar represents the median protein level. Protein expression level of procaspase-2 quantitated in 21 B-lineage ALL samples (○), 13 T-lineage ALL samples (•), and 10 AML samples (▾). (B) Procaspase-2 expression versus in vitro PRED, VCR, and ASP (PVA) resistance in childhood acute lymphoblastic leukemia. The protein expression level of PARP quantitated in 16 PVA-sensitive (S) and 18 PVA-resistant (R) patients with B-lineage ALL (○) or T-lineage ALL (•). ^*Statistically significant after Bonferroni correction for multiple comparisons.