Figure 4.
Figure 4. Splenic hypofunction in M33-KO mice. Peripheral blood smears were prepared on slide glasses, and erythrocytes containing Howell-Jolly bodies were counted. Percentage of the erythrocytes containing Howell-Jolly bodies is presented for M33-KO (–/–) and wild-type (+/+) animals and demonstrates splenic hypofunction in M33-KO mice. Data represent means ± SD of 3 wild-type and 4 M33-KO spleens (A). The expressions of F4/80 were compared immunohistochemically among wild-type (B), M33-KO (C), and Ad4BP/SF1-KO (D) spleens at 18.5 days after coitus. Scale bar, 50 μm.

Splenic hypofunction in M33-KO mice. Peripheral blood smears were prepared on slide glasses, and erythrocytes containing Howell-Jolly bodies were counted. Percentage of the erythrocytes containing Howell-Jolly bodies is presented for M33-KO (–/–) and wild-type (+/+) animals and demonstrates splenic hypofunction in M33-KO mice. Data represent means ± SD of 3 wild-type and 4 M33-KO spleens (A). The expressions of F4/80 were compared immunohistochemically among wild-type (B), M33-KO (C), and Ad4BP/SF1-KO (D) spleens at 18.5 days after coitus. Scale bar, 50 μm.

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