Figure 3.
![Figure 3. Intravenous injection of MSCs ameliorates EAE. MSCs injected at days 3 and 8 after immunization (▪) halt disease severity compared with controls (▵) (P < .05 from day 17 onward). No differences were observed between controls and mice treated at day 24 after immunization (▴) (A). Administration of MSCs at day 10 (▪) or at day 15 (▴) after immunization, after disease onset, ameliorates EAE (P < .05 from day 22 [*] for mice treated at day 10 and from day 30 [§] for mice treated at day 15 compared with controls [▵] by Mann-Whitney U test) (B). Arrows indicate days of MSC injection.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/106/5/10.1182_blood-2005-04-1496/6/zh80170583590003.jpeg?Expires=1735562963&Signature=JnhOi1VPNTsAdmASZQfiiTp3vfCRaHsXF9NYaLD83kF9Ddp~r-26H~6aTLxkvjp73PcIxE2Pj24zV8eIWohdcYCw3Ag6cMSA1h~wfK1EtLTEjgWZFjbppAjQdzumjczae8m3gu4DlUM1xCshWR~97xSVzuUznRYEiy1daGpu4xDP-Mbm8xdrE-rGo7l2TctqO8PGRlqryfYpGFWpDVyGcXuWWdN0Mm1vqxNA~50vgYAc2vDPTK9xcRpV1j1vor399PlDYLWHbQUBnnV2NN9hWI2zodjikpCdvoUwTcX-FLShvwu9Ui5GsRLO3ru9uhEUyJv7YSzEB67UQ6bv-bGgVQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Intravenous injection of MSCs ameliorates EAE. MSCs injected at days 3 and 8 after immunization (▪) halt disease severity compared with controls (▵) (P < .05 from day 17 onward). No differences were observed between controls and mice treated at day 24 after immunization (▴) (A). Administration of MSCs at day 10 (▪) or at day 15 (▴) after immunization, after disease onset, ameliorates EAE (P < .05 from day 22 [*] for mice treated at day 10 and from day 30 [§] for mice treated at day 15 compared with controls [▵] by Mann-Whitney U test) (B). Arrows indicate days of MSC injection.
