Schema of Children’s Oncology Group (C.O.G.) Protocol #AAML0122 for newly diagnosed JMML patients. Protocol is overseen by NCI-CTEP.

Abbreviations: FTI, farnesyltransferase inhibitor; Ara-C, cytosine arabinoside; RA, retinoic acid; JMML, juvenile myelomonocytic leukemia; NCI-CTEP, National Cancer Institute – Cancer Therapy Evaluation Program.