Chromosome aberrations in acute lymphoblastic leukemia (ALL) as (reverse transcriptase) polymerase chain reaction [(RT-)PCR] targets for minimal residual disease (MRD) detection.a
a The detection limit of PCR analysis of chromosome aberrations is 10–4 to 10–6.
b The indicated percentages represent frequencies within the precursor-B-ALL and T-ALL groups.
c In infant ALL, the frequency of t(4;11) can be as high as 50% and the total group of 11q23 aberrations as high as 70%.
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