Figure 1.
von Willebrand factor.
(A) mRNA showing the propeptide, designated gene regions (A–D), and below, locations where clusters of mutations occur in different types of VWD.
(B) Mature VWF peptide subunit (monomer) showing amino acid numbers (aa) and functional binding domains for ligands.
Abbreviations: mRNA, messenger RNA; VWD, von Willebrand disease; VWF, von Willebrand factor.