Delayed regression of metastatic renal cell carcinoma (RCC) following a nonmyeloablative transplant.

A) Extensive metastatic renal cell carcinoma (clear cell histology) involving the lungs had grown slightly 1 month after a nonmyeloablative transplant. B) Complete regression of metastatic disease following cyclosporine withdrawal 4 months after transplantation consistent with a graft-versus-tumor (GVT) effect. Disease remission is ongoing more than 5 years after the transplant.