(in Carmel et al). Major pathways for remethylation and transsulfuration of homocysteine and related metabolic pathways, showing substrates, cofactors and enzymes.

Abbreviations: MS, methionine synthase; CbS, cystathionine beta synthase; MTHFR, methylenetetrahydrofolate reductase; DHFR, dihydrofolate reductase; TS, thymidylate synthase; THF, tetrahydrofolate.