(in Carroll et al) . A. Three intrinsic biologic clusters of infants were distinguished by VxInsight and through PCA (not shown). In each cluster, each individual patient is represented by a pyramid. B. Each case was queried for the presence of ALL (white pyramids) vs. AML (green pyramids) morphology (appreciated better in Figure 1C, to the right) and the presence of chromosomal rearrangements involving the MLL gene (shown as blue pyramids). C. ANOVA was used to identify the most statistically significant genes that were unique to each cluster and which could be used to distinguish each cluster.