(in Diehl et al). NF-κB–dependent gene profiling in HRS cells (L428 cells [black bars] and HDLM2 cells [red bars]).
Potential target genes, which fit the criteria for decreased/increased genes upon NF-κB inhibition in both cell lines, are grouped based on their molecular functions.
Reprinted with permission from
Hinz M, Lemke P, Anagnostopoulos I, et al. Nuclear factor kappaB-dependent gene expression profiling of Hodgkin’s disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity. J Exp Med. 2002;196:605–617.
by copyright permission of The Rockefeller University Press.