Effect of a single bolus infusion (0.4 g/kg) of IVIg on IL-10 production in PBMCs from 8 patients with HIV infection. PBMCs were prepared from blood samples taken at the indicated time points before and after IVIg infusion and cultured without stimulation (A) or with anti-CD40 monoclonal antibody (B). Supernatants were harvested after 7 days and assayed for IL-10 by ELISA. Data are given as medians and 25th and 75th percentiles. *P < .05 versus levels before infusion (0 hours).