Fig. 4.
![Fig. 4. Different effects between group I and group II antagonists on [Ca2+]i changes induced by thrombin. Platelets were preincubated with 10 μmol/L of each antagonist and then stimulated with 0.03 U/mL thrombin. (A) None. (B) FK633 (group I). (C) FR169824 (group I). (D) Ro44-9883 (group II). (E) MK383 (group II). AG and Ca2+ indicate aggregation curve and trace of changes in [Ca2+]i, respectively. These results are representative of two separate experiments.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/92/10/10.1182_blood.v92.10.3675/4/blod42238004x.jpeg?Expires=1735552015&Signature=hDqcUXrmYvHeZZgmBSTDjV1o4n9NfyGejzJWRSR4KDhmCWgFEQLu-erV9BrAUD3XmpAXos9dDreFWhor5j5Fj6Xug2-R-MZTDaAkHTGjYpdr7YntH9g53EDhn8upFKBjvLGIK8YcsmFdpw8y6D85ma6eKndU1~tzyuiwiPYHolaq9IggRH-JjkgnKaobsu7w38bTHIMsy0nHndiCrHyGVxB6xx36f~WnoEcNpBEGhEGbXVb6TRiZF8OWolPGZECtFOZg02f09fMiw01BC6KmYkncEjlSIGel0LGyU4~kYfpY9fxr7EtklaTb~EgwufYhXkiOzoaICUSSZOGQQZICJA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Different effects between group I and group II antagonists on [Ca2+]i changes induced by thrombin. Platelets were preincubated with 10 μmol/L of each antagonist and then stimulated with 0.03 U/mL thrombin. (A) None. (B) FK633 (group I). (C) FR169824 (group I). (D) Ro44-9883 (group II). (E) MK383 (group II). AG and Ca2+ indicate aggregation curve and trace of changes in [Ca2+]i, respectively. These results are representative of two separate experiments.
