Fig. 6.
Inhibition of the second [Ca2+]i peak induced by group I with aspirin, BM13505, or apyrase. The second peak of [Ca2+]i induced by 10 μmol/L FK633 and 0.03 U/mL thrombin was inhibited by 100 μmol/L aspirin (cyclooxygenase inhibitor), 10 μmol/L BM13505 (TXA2receptor antagonist), or 0.5 U/mL apyrase (ADP scavenger). (a and d) 10 μmol/L FK633; (b) 10 μmol/L FK633 plus 100 μmol/L aspirin; (c) 10 μmol/L FK633 plus 10 μmol/L BM13505; (e) 10 μmol/L FK633 plus 0.5 U/mL apyrase. These results are representative of two separate experiments.