Fig. 1.
KGF treatment and conditioning schedule for BMT experiments. KGF (5 mg/kg/d) or PBS was administered sc to B10.BR recipients on days −6, −5, and −4. Mice were then further segregated into those receiving Cy (120 mg/kg/d) or PBS intraperitoneally on days −3 and −2. All recipients were irradiated (7.5 Gy) on the day before transplant (day −1). Groups were segregated into those receiving C57BL/6 BM alone or BM with allogeneic spleen cells (BMS) intravenously. In some mice, KGF treatment was also administered on days 1, 2, and 3 posttransplant in the context of Cy/TBI conditioning.