Fig. 3.
Fig. 3. Amelioration of mortality (A) and weight loss (B) by KGF after allogeneic BMT with a uniformly 100% lethal dose of allogeneic spleen cells. B10.BR recipient mice (n = 26/group) were lethally irradiated (7.5 Gy) on day −1 and infused on day 0 with C57BL/6 BM either without (BM) or with 15 × 106 spleen cells (BMS) as indicated. Groups were further segregated into those receiving PBS or KGF (5 mg/kg/d) on days −6, −5, and −4 pre-BMT. Data compiled from two representative experiments are shown. For (A), (□) BM ± KGF, (▪) BMS + PBS, and (▴) BMS + KGF. For (B), (□) BM + PBS, (▵) BM + KGF, (▪) BMS + PBS, and (▴) BMS + KGF.

Amelioration of mortality (A) and weight loss (B) by KGF after allogeneic BMT with a uniformly 100% lethal dose of allogeneic spleen cells. B10.BR recipient mice (n = 26/group) were lethally irradiated (7.5 Gy) on day −1 and infused on day 0 with C57BL/6 BM either without (BM) or with 15 × 106 spleen cells (BMS) as indicated. Groups were further segregated into those receiving PBS or KGF (5 mg/kg/d) on days −6, −5, and −4 pre-BMT. Data compiled from two representative experiments are shown. For (A), (□) BM ± KGF, (▪) BMS + PBS, and (▴) BMS + KGF. For (B), (□) BM + PBS, (▵) BM + KGF, (▪) BMS + PBS, and (▴) BMS + KGF.

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