KGF delays the Cytoxan-induced acceleration of mortality (A) and weight loss (B). B10.BR recipient mice (n = 26/group) were lethally irradiated (7.5 Gy) on day −1 and infused on day 0 with C57BL/6 BM either without (BM) or with 15 × 10⁶ spleen cells (BMS) as indicated. Groups treated with Cy received 120 mg/kg/d on days −3 and −2. Groups were further segregated into those receiving PBS or KGF (5 mg/kg/d) on days −6, −5, and −4 pre-BMT. Data compiled from two representative experiments are shown. For (A), (○) BM + CY + PBS, (▵) BM + CY + KGF, (•) BMS + CY + PBS, and (▾) BMS + CY + KGF. For (B), (○) BM + CY + PBS, (▵) BM + CY + KGF, (•) BMS + CY + PBS, and (▾) BMS + CY + KGF. *P < .05 versus no KGF.