Schematic representation of predicted AF4 gene structure. The relative location and size of C9, C15, and PL12 as compared with AF4 gene are shown as dark lines; alternate splicing sites, breakpoints of t(4;11) translocations, nuclear localization sequences (NSL), and GTP binding motifs of AF4 are indicated. The figure was constructed based on the data from Morrissey et al,2 Frestedt et al,9 Tkachuk et al,11 and Hilden et al.22