Fig. 1.
(A) Allele frequencies for the TNFd microsatellite polymorphism as measured in this study (80 Allo BMT recipients, 160 alleles) and two other published reports (Udalova et al10and Turner et al12). Results on a panel of 28 unselected normals (56 alleles) are also shown. The observed allele frequencies show similar frequencies to those reported elsewhere, indicating that the appropriate allele designations/identifications were being made. The frequency of predicted d3/d3 homozygotes of 23.1 (predicted from the allele frequency by Hardy-Weinberg equilibrium) compared well with the observed frequency of 26. (□) HT panel (210); (▧) heart transplants (44); (▪) BMT (160); (▧) 28 normals (56). (B) Allele frequencies for the IL-10 −1064 microsatellite as measured in this study (80 allo-BMT recipients, 160 alleles) plus frequencies from two other studies (Eskdale and Gallagher19and Worthington et al, personal communication, 1998). The observed allele frequencies show similar frequencies to those reported elsewhere, indicating that the appropriate allele designations/identifications were being made. The frequency of genotypes predicted from the allele frequencies by Hardy-Weinberg equilibrium compare well with the observed frequencies (i9/9 predicted 14.45, observed 15; i9/13 predicted 12.75, observed 13). (□) Gallagher (204); (▧) Worthington; (▪) BMT (160).