Fig. 1.
Extramedullary hematopoiesis in 8-week-old mi/miand Fos (−/−) mice.
The numbers of colony-forming cells elicited by 100 U/mL IL-3 or 20 U/mL IL-7 per 105 cells from bone marrow, spleen, liver, thymus, peripheral lymph nodes (cervical, axillary, and inguinal), mesenteric lymph nodes, Peyer patches, and peritoneal cavity were measured. Cells from tissues other than bone marrow, spleen, and liver did not form any colonies (< 1/105). Data are expressed as the mean ± SD of triplicate cultures. *Values of osteopetrotic mice that are significantly different from those of the corresponding normal littermates (P < .05).
