Engraftment of CD34⁺ cells within the sheep bone marrow (BM) following in utero HSC transplantation.

To determine whether cotransplanting stromal cells with the HSC graft produced early donor cell differentiation within the periphery by inducing all of the grafted HSC to undergo terminal differentiation, BM was obtained from animals killed at 3, 6, and 9 weeks after transplant and analyzed by flow cytometry for the presence of CD34. Values shown represent the mean ±  1 SEM.