Fig. 8.
Effect of PP1, PD098059, wortmannin, and LY294002 on LTB4-induced chemotaxis.
Cells were preincubated for 5 minutes at 37°C in the presence of the indicated concentration of (A) PP1, (B) PD098059, (C) wortmannin, and (D) LY294002. Following stimulation of eosinophils with LTB4 (100 nmol/L), chemotaxis was determined at 3 hours. The effect of the inhibitor is expressed as a percentage of the maximal response. Data represent the mean ± SEM of 3 to 6 independent experiments.
