Signal transduction in a CAR T cell. Similar to IL-2 signaling, the introduction of an Epo receptor to a CAR T cell provides signal 3, which synergizes with signals 1 and 2 generated by the CAR molecule to promote CAR T-cell function and efficacy.
Signal transduction in a CAR T cell. Similar to IL-2 signaling, the introduction of an Epo receptor to a CAR T cell provides signal 3, which synergizes with signals 1 and 2 generated by the CAR molecule to promote CAR T-cell function and efficacy.