Figure 7.
Graphical representation of exome sequencing of T2ΔT3 and ΔT2T3 mice on IGV. IGV-inspected sequence reads of Tet2 locus in T2ΔT3 mice (A) and on Tet3 locus in ΔT2T3 mice (B) are shown for BM (red) and tail (blue) DNA. Note that the absence of reads is shown for exon 11 of Tet2 in leukemic BM of T2ΔT3 mice (n = 6; panel A) and for exons 8 and 9 of Tet3 in leukemic BM of T2ΔT3 mice (n = 6; panel B). Reads were present in the BM of 2 T2ΔT3 mice (#47 and #60).