Differential expression of genes in granulocytes and platelets of PV patients compared with controls. Differentially expressed genes (adjusted P < .05; log₂ fold change >1) in granulocytes (A) and platelets (B) of PV patients compared with controls were analyzed using the DEseq2 package. There were 2 groups in PV patients (group 1 and group 2). In granulocytes, patients in group 1 had less JAK2^V617F positivity than those in group 2; whereas in platelets, there was no difference in JAK2^V617F positivity, white blood cell counts, platelet counts, or type of treatment between group 1 and group 2.