Relative expression levels of the tested genes in patients treated with hydroxyurea and pegylated IFN-α. Relative gene expression levels were determined by qRT-PCR in granulocytes (A) and platelets (B) of controls and patients. *P < .05; **P < .01; ***P < .001. Cont, controls (n = 28); HU, treated with hydroxyurea (n = 24); IFN-α, treated with pegylated interferon α (n = 16); NoTx, no treatment (n = 14).