Gene expression analysis of genes recurrently altered in B- and T-ALL. (A) Gene expression analysis of all B-ALL samples analyzing expression of ABL1, JAK2, KMT2A, IL3, and CRLF2. Plots show gene names on the x-axis and gene expression (log₂ [counts +1]) on the y-axis. Box plots show mean and interquartile range. Samples in which a fusion was identified by RNA-seq involving that particular gene are green. Samples containing rearrangements involving IGH are pink and were missed by RNA-seq (IGHr). All other samples that contain gene fusions missed by RNA-seq are red (Missed). (B) Gene expression analysis of all T-ALL samples showing expression levels of MYC and TLX1. Plots show gene name on the x-axis and gene expression (log₂ [counts +1]) on the y-axis. Box plots show mean and interquartile range. Samples in which a fusion was identified by RNA-seq involving MYC or TLX1 are light pink or pink, respectively. All remaining samples are gray.