Gene expression classifier enriches for response to avadomide in DLBCL. (A) Heat map showing application of the gene expression classifier to the CC-122-ST-001 trial dataset. (B) Classifier status at screening in 69 R/R DLBCL patients enrolled in a trial of avadomide monotherapy (32 classifier-positive; 37 classifier-negative) showed a significant correlation with PFS. (C) Classifier status did not correlate with outcome in R/R DLBCL patients treated with rituximab-containing chemotherapy.²⁰ .