Figure 1.
![Study design. (A) Patient cohort of the retrospective derivation study, May 2014 to August 2015 (n = 221 [22 HIPA-positive cases]). (B) Patient cohort of the prospective derivation study, September 2015 to December 2016 (n = 305 [26 HIPA-positive cases]). 1CLIA ≥0.13 U/mL. (C) Standards for the Reporting of Diagnostic Accuracy Studies flowchart of the patient cohort of the prospective validation study, January 2017 to November 2019 (n = 687 [53 HIPA-positive cases]).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/135/14/10.1182_blood.2019002845/2/bloodbld2019002845f1.png?Expires=1735496356&Signature=khPXIOWi4XFKIgMwFVBq1qDHAuM58i6tCx6LDw6FAwlnl53sedzBFSLkfZYLehGSiXP6kxgyOuTXpx-9C2Eb17JY-d0lvdfux03PLDySSlw9YoeJRxLykocBd-UncxgRo7bNS3Y9~hfFTBT4YfhPoS07oTWt5GaXvzguAQjR~m3GhZKXolZrBWjJmiPEVgWby62cGZYFpjpSbkcdcSAyE1-ezqbzwQUvLj5QuHn7LWM6QBQ7Pst6kn3~Qqr30QSflkt2ZRrzX2jPwVTvDwYeT6EWNKVNPqE-EiDSK35EcJ6FoqcT19bpZLGzR8766VGwLx08K5ZI-6lssNv-8i40AQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Study design. (A) Patient cohort of the retrospective derivation study, May 2014 to August 2015 (n = 221 [22 HIPA-positive cases]). (B) Patient cohort of the prospective derivation study, September 2015 to December 2016 (n = 305 [26 HIPA-positive cases]). 1CLIA ≥0.13 U/mL. (C) Standards for the Reporting of Diagnostic Accuracy Studies flowchart of the patient cohort of the prospective validation study, January 2017 to November 2019 (n = 687 [53 HIPA-positive cases]).