Figure 4.
Simon-Makuch plot for RFS. (A) Analysis includes 119 patients in CR/CRh/CRi from date of first response, of which, 82 eventually received consolidation cycles (4 other consolidation patients did not achieve CR/CRh/CRi in first 2 cycles and were not included in in this analysis). Median (95% CI) is 8.8 (7.6 to 9.9) months in the no-consolidation group and 7.6 (3.7-11.6) months in the consolidation group. (B) Analysis includes 63 patients alive and in CR/CRh/CRi 5 months after first hematological response, of which, 34 eventually received maintenance cycles (2 other maintenance patients relapse before 5 months and were not included in this analysis). Median (95% CI) is 9.8 (8.5-11.1) months in the no-maintenance group and 14.5 (7.1-21.9) months in the maintenance group.