Acquired somatic mutations in myeloid cancer and AA-related genes in relation to EPAG treatment. Targeted deep sequencing and/or WES was performed on bone marrow cells from 64 patients. Detection of acquired variants in a panel of genes with somatic mutations associated with myeloid cancer or AA are shown. Each row indicates a specific MC/AA gene and each column a patient, with results shown for baseline and primary end point (3 months for study 1, 6 months for study 2). The panel of MC/AA genes is given in the supplemental Methods, and the mutations detected are listed in supplemental Table 8.