Relation between platelet count and bleeding manifestations. The frequency of bleeding manifestations is expressed as the percentage of patients with the indicated bleeding manifestation for every 5000 platelet counts. Skin purpura (A); gingival bleeding (B); epistaxis (C); hematuria (D); melena (E); ICH (F). Patients with a platelet count ≥50 × 10⁹/L were grouped together. The linear and curved line in each graph represents the overall change in the bleeding frequency. Note that each graph has a different y-axis scale.