Correlation between increasing EFS and decreasing use of health care for all patients. Overall use of health care per month of OS (A), combined clinic visits, ER visits, hospitalizations, and consultations per month of OS (B), combined invasive procedures, imaging, and laboratory studies per month of OS (C), and blood product transfusions per month of OS (D). Overall use of health care consisted of the sum of the number of clinic visits, ER visits, hospital admissions, consultations, blood product transfusions, laboratory studies, imaging studies, and invasive procedures. Blood product transfusions included packed red blood cell and platelet transfusions.