Figure 6.
The mAb 1C9 inhibits hemolysis mediated by activated complement from rhesus monkeys but not from mice. (A) Ten nM of 1C9 or mouse IgG (mIgG) was incubated with EshA and 1% sera from 9 individual rhesus monkeys. Hemolysis was measured by reading the optical density at 450 nm (OD450). (B) Ten μM of 1C9 or mIgG was incubated with Erabb and 10% sera from 5 individual C57BL/6 mice. Hemolysis was measured by reading the OD414. *P < .05.

The mAb 1C9 inhibits hemolysis mediated by activated complement from rhesus monkeys but not from mice. (A) Ten nM of 1C9 or mouse IgG (mIgG) was incubated with EshA and 1% sera from 9 individual rhesus monkeys. Hemolysis was measured by reading the optical density at 450 nm (OD450). (B) Ten μM of 1C9 or mIgG was incubated with Erabb and 10% sera from 5 individual C57BL/6 mice. Hemolysis was measured by reading the OD414. *P < .05.

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