Nascent proteome analysis reveals SNORD42A-dependent protein translation. (A) The volcano plot indicates the log-fold change (log2FC; horizontal axis) and P value (vertical axis) from nascent proteomics in SNORD42A knockout and control single clones. (B) GSEA demonstrated that most ribosomal proteins are depleted following a SNORD42A knockout. FDR, false discovery rate; NES, normalized enrichment score. (C) GSEA of genes with known IRES activity. (D) The graph shows the GO enrichment analysis.