Figure 4.
Patients with MDS-PA display altered T-cell regeneration after autologous transplant. (A) Identification of various T-cell subsets using multidimensional flow cytometry and principal component analysis (PCA) in patients with (n = 9) or without (n = 33) MDS-PA: naive, central memory, effector memory, transitional memory, and terminally differentiated CD4 T cells, CCR7-negative and CCR7-positive Tregs, naive, central memory, effector memory, effector, and terminally differentiated CD8 T cells, as well as naive and effector memory TCRγδ T cells. Percentages of γδ naive T cells within total γδ T cells (B), CD4 and CD8 central memory within their respective CD4 and CD8 compartments (C), and CCR7-negative and CCR7-positive subsets within Tregs (D). *P ≤ .05; **P ≤ .01.