Figure 3.
Tables and forest plots of AP and BP transformations during study treatment. ENEST RCT sensitivity analysis: 300 mg of nilotinib, 400 mg of nilotinib, and mean values of 300 mg and 400 mg of nilotinib. Nilotinib ENEST (NCT00471497; 300 mg and 400 mg). In ENEST RCT, the patients were randomly assigned to receive 300 mg of nilotinib (n = 282), 400 mg of nilotinib (n = 281), 400 mg of imatinib (n = 283); the number of events is presented for the 3 groups (300 mg of nilotinib, 400 mg of nilotinib, 400 mg of imatinib). The sensitivity analysis was made by introducing into the meta-analysis: first, the results of 300 mg of nilotinib (A); second, the results of 400 mg of nilotinib (B); and third, the arithmetic mean of the results of the 2 nilotinib doses (C).