Differentially mutated genes between rrDLBCL and untreated DLBCL. (A) Mutation type and frequency of each differentially mutated gene in the untreated and rrDLBCL cohorts, using a significance threshold of 0.1 following false discovery rate correction. Untreated cases with insufficient coverage (not callable) in the gene of interest were not counted in the denominator for that gene (supplemental Methods). (B) Forest plot showing the odds ratio for all differentially mutated genes, as determined by the Fisher’s exact test, for all differentially mutated genes (supplemental Table 6). CI, confidence interval.