Characterization of revertant CD8⁺T cells. (A) Histograms showing the presence of a revertant ARPC1B⁺ population in CD4⁺ and CD8⁺ compartments in freshly isolated PBMCs of P1 (red line) as compared with HC (dashed line). Blue line: negative control. Box represents the percentage of ARPC1B⁺ cells in naïve, central memory (CM), TSCM (CD3⁺CD8⁺CD45RA⁺CD62L⁺CD95⁺), EM (CD3⁺CD8⁺CD45RA⁻CD62L⁻), and TEMRA (CD3⁺CD8⁺CD45RA⁺CD62L⁻) gated on CD8⁺ T cells. P1, black line; HC, dashed line; negative control, blue line. (B) Determination of Vβ in gated CD3⁺CD8⁺ARPC1B⁺ T cells in P1 (red bars) and P6 (blue bars) as compared with HC (gray bars, n = 3). Mean ± SD. Arrows indicate relative expansion of Vβ.