Figure 6.
Figure 6. Preferential migration of revertant CD8+ T cells. (A) Electropherograms showing homozygous peaks in CD4+CD8−ARPC1B− and CD4−CD8+ARPC1B− and heterozygous peak in CD4−CD8+ARPC1B+ in sorted subpopulations in PHA T-cell lines of P1 as compared with bulk population in a HC. The site of second mutation is indicated in red. (B) Ratio of migrated ARPC1B+CD8+ (red) and ARPC1B−CD8+ (blue) T cells at to SDF1-α as compared with HC (n = 6, shaded area). Mean ± SEM. Input: percentage of T cells expressing ARPC1B before migration.

Preferential migration of revertant CD8+T cells. (A) Electropherograms showing homozygous peaks in CD4+CD8ARPC1B and CD4CD8+ARPC1B and heterozygous peak in CD4CD8+ARPC1B+ in sorted subpopulations in PHA T-cell lines of P1 as compared with bulk population in a HC. The site of second mutation is indicated in red. (B) Ratio of migrated ARPC1B+CD8+ (red) and ARPC1BCD8+ (blue) T cells at to SDF1-α as compared with HC (n = 6, shaded area). Mean ± SEM. Input: percentage of T cells expressing ARPC1B before migration.

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