Continuation of CNI instead of discontinuation improved the outcome of TA-TMA patients. (A) The survival time after TA-TMA onset of the individual patients are shown as bar graphs. TA-TMA patients were divided into 4 groups based on their status of immunosuppressant modulation. The survival status (alive or dead) of each patient is shown at the bottom. The median number of days of OS and 95% CI in each group are displayed. (B) OS after TA-TMA onset was more favorable in the patients who continued the CNI treatment (maintenance/reduction) or were switched to other CNIs than in those for whom CNIs were replaced with CS (switch to CS).