Figure 3.
Abstract representation of BMT samples. (A) A total of 9 megakaryocytic phenotypes were automatically discovered in the unsupervised clustering analysis. Morphological representation characterized by proportions and heterogeneity of the megakaryocytic phenotypes (B) and topographical distribution (C) can be used to describe a BMT sample in the form of a radar plot (D). In total, we analyzed 17 features, 9 of which were related to the proportions of the megakaryocyte phenotypes and visualized in the form of morphological similarities to megakaryocytes in different subgroups of MPNs or reactive cases (highlighted in orange on the radar plot).