NK cell functional tests. (A) Degranulation evaluated by CD107/LAMP expression on NK cell surface after activation by K562 and Ig-coated P815 target cells. (B) IFN-γ–producing NK cells after activation by K562 and Ig-coated P815 target cells. Each point represents an outlier (error bars, 10th and 90th percentiles; box plots, median values and 25th and 75th percentiles). ***P < .001, ****P < .0001 by Mann-Whitney U test (2 groups) and Kruskal-Wallis test (3 groups). ns, not significant.